Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled …

…, AF Marques, L Izquierdo, SS Sender… - The Lancet Infectious …, 2018 - thelancet.com
Background Chagas disease is a major neglected vector-borne disease. In this study, we
investigated the safety and efficacy of three oral E1224 (a water-soluble ravuconazole prodrug…

[HTML][HTML] Cyclin-dependent kinase inhibitors in hematological malignancies—current understanding,(pre-) clinical application and promising approaches

A Richter, N Schoenwaelder, S Sender, C Junghanss… - Cancers, 2021 - mdpi.com
… Further, S phase transition was suppressed and Rb and FOXM1 dephosphorylation was
observed. In vivo, PROTAC YX-2-107 achieved a comparable or better reduced leukemia …

[HTML][HTML] Safety, immunogenicity, and efficacy of the BNT162b2 Covid-19 vaccine in adolescents

…, JL Perez, EB Walter, S Senders… - … England Journal of …, 2021 - Mass Medical Soc
Background Until very recently, vaccines against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) had not been authorized for emergency use in persons younger than …

Supporting individuals with intellectual and developmental disability during the first 100 days of the COVID‐19 outbreak in the USA

WR Mills, S Sender, J Lichtefeld… - Journal of …, 2020 - Wiley Online Library
Background It is unknown how the novel Coronavirus SARS‐CoV‐2, the cause of the current
acute respiratory illness COVID‐19 pandemic that has infected millions of people, affects …

Carbonic Anhydrase in the Gills of Seawater-and Freshwater-acclimated Flounders Platichthys flesus: Purification, Characterization, and Immunohistochemical …

S Sender, K Böttcher, Y Cetin… - … of Histochemistry & …, 1999 - journals.sagepub.com
Flounders Platichthys flesus were investigated with respect to isolation, purification, and
cellular localization of carbonic anhydrase (CA) in the respiratory system. CA was purified from …

[HTML][HTML] Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids

…, N Saul, AA Cohen, R Köhling, S Sender… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… FUNDING: This project has received funding from the European Union’s Horizon 2020
research and innovation programme under Grant agreement No 633589 (Aging with Elegans). …

Heart and Respiratory Rates and Their Significance for Convective Oxygen Transport Rates in the Smallest Mammal, the Etruscan Shrew Suncus Etruscus

…, R Fons, T Peters, S Sender - Journal of experimental …, 1996 - journals.biologists.com
… The ambient temperature of 22 C that we used is the mean temperature that S. etruscus
encounters when resting in its nest within the stone walls of the vineyards around Banyuls-sur-…

Best practices in adolescent and young adult patients with acute lymphoblastic leukemia: a focus on asparaginase

N Boissel, LS Sender - Journal of adolescent and young adult …, 2015 - liebertpub.com
The inclusion of asparaginase in chemotherapy regimens to treat acute lymphoblastic
leukemia (ALL) has had a positive impact on survival in pediatric patients. Historically, …

Rates of rewarming, heart and respiratory rates and their significance for oxygen transport during arousal from torpor in the smallest mammal, the Etruscan shrew …

R Fons, S Sender, T Peters… - Journal of experimental …, 1997 - journals.biologists.com
… Since warm-up rates are higher in S. etruscus than in any other … oxygen transport systems
of S. etruscus are adapted to the … muscle activity in S. etruscus begins at T b >17 C (Fig. 1). …

FGF23-associated tumor-induced osteomalacia in a patient with small cell carcinoma: a case report and regulatory mechanism study

…, J Choe, V Chang, S Sender… - … journal of surgical …, 2016 - journals.sagepub.com
… of FGF23, RT-PCR for multiple key molecules in the FGF1-FGFR1 loop and the wnt signaling
pathway was performed on fresh tumor tissue acquired from autopsy, with the patient’s