… adapt material from JR Flynn, ‘‘Efeito Flynn: Repensando a inteligeˆncia e seus efeitos’’ [The
Flynn effect: Rethinking intelligence and what affects it], in C. Flores-Mendoza & R. Colom (…

In recent years, long noncoding RNAs (lncRNAs) have emerged as an important class of
regulators of gene expression. lncRNAs exhibit several distinctive features that confer unique …

This paper applies a theory-driven approach to explore why the use of patient-reported
outcome (PRO) measures in clinical practice, in particular, health-related quality of life (HRQoL) …

This book provides a comprehensive source of information on all groups of parasites which
occur spontaneously in animals likely to be maintained in laboratories. It was compiled by …

Innate immunity provides the first line of defence against invading pathogens and provides
important cues for the development of adaptive immunity. Type-2 immunity—responsible for …

The genome is extensively transcribed into long intergenic noncoding RNAs (lincRNAs),
many of which are implicated in gene silencing 1 , 2 . Potential roles of lincRNAs in gene …

Cell-fate transitions involve the integration of genomic information encoded by regulatory
elements, such as enhancers, with the cellular environment 1 , 2 . However, identification of …

Recruitment of the RNA polymerase II (Pol II) transcription initiation apparatus to promoters
by specific DNA-binding transcription factors is well recognized as a key regulatory step in …

Several of the thousands of human long non-coding RNAs (lncRNAs) have been
functionally characterized 1 , 2 , 3 , 4 ; however, potential roles for lncRNAs in somatic tissue …

Transcription initiation by RNA polymerase II (RNAPII) is thought to occur unidirectionally
from most genes. Here, we present evidence of widespread divergent transcription at protein-…