[HTML][HTML] Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
[PDF][PDF] SELFIES and the future of molecular string representations
Artificial intelligence (AI) and machine learning (ML) are expanding in popularity for broad
applications to challenging tasks in chemistry and materials science. Examples include the …
applications to challenging tasks in chemistry and materials science. Examples include the …
Antibiotics for exacerbations of chronic obstructive pulmonary disease
DJ Vollenweider, A Frei… - Cochrane Database …, 2018 - cochranelibrary.com
Background Many patients with an exacerbation of chronic obstructive pulmonary disease (COPD)
are treated with antibiotics. However, the value of antibiotics remains uncertain, as …
are treated with antibiotics. However, the value of antibiotics remains uncertain, as …
Direct identification of ligand-receptor interactions on living cells and tissues
Many cellular responses are triggered by proteins, drugs or pathogens binding to cell-surface
receptors, but it can be challenging to identify which receptors are bound by a given ligand…
receptors, but it can be challenging to identify which receptors are bound by a given ligand…
[HTML][HTML] Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans
…, A Rehman, SJ Ott, C Steurer-Stey, A Frei, P Frei… - PloS one, 2013 - journals.plos.org
Background The human intestinal microbiota is a crucial factor in the pathogenesis of
various diseases, such as metabolic syndrome or inflammatory bowel disease (IBD). Yet, …
various diseases, such as metabolic syndrome or inflammatory bowel disease (IBD). Yet, …
Examination of change factor methodologies for climate change impact assessment
A variety of methods are available to estimate values of meteorological variables at future
times and at spatial scales that are appropriate for local climate change impact assessment. …
times and at spatial scales that are appropriate for local climate change impact assessment. …
Early postoperative enteral immunonutrition: clinical outcome and cost-comparison analysis in surgical patients
…, G Spath, D Wulfert, U Joosten, A Frei… - Critical care …, 1997 - journals.lww.com
Objective To determine if early postoperative feeding of patients with upper gastrointestinal
malignancy, using an enteral diet supplemented with arginine, dietary nucleotides, and …
malignancy, using an enteral diet supplemented with arginine, dietary nucleotides, and …
Highly multiplexed simultaneous detection of RNAs and proteins in single cells
To enable the detection of expression signatures specific to individual cells, we developed
PLAYR (proximity ligation assay for RNA), a method for highly multiplexed transcript …
PLAYR (proximity ligation assay for RNA), a method for highly multiplexed transcript …
Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study
…, A Domenghino, HE Aschmann, A Frei… - bmj, 2023 - bmj.com
Objective To evaluate longer term symptoms and health outcomes associated with post-covid-19
condition within a cohort of individuals with a SARS-CoV-2 infection. Design …
condition within a cohort of individuals with a SARS-CoV-2 infection. Design …
Towards improvement of marker assisted selection of apple scab resistant cultivars: Venturia inaequalis virulence surveys and standardization of molecular marker …
A Patocchi, A Frei, JE Frey, M Kellerhals - Molecular Breeding, 2009 - Springer
Molecular breeding for pathogen resistance faces two major problems that delay its widespread
adoption, resistance breakdown and difficulties in unambiguously identifying the alleles …
adoption, resistance breakdown and difficulties in unambiguously identifying the alleles …