[HTML][HTML] What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium?

SC Satchell, JE Tooke - Diabetologia, 2008 - Springer
Microalbuminuria is an important risk factor for cardiovascular disease and progressive renal
impairment. This holds true in the general population and particularly in those with diabetes…

Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier

SC Satchell, F Braet - American Journal of Physiology …, 2009 - journals.physiology.org
… The earliest GEnC arise from mesenchyme (or angioblasts, endothelial precursors) migrating
into the cleft of the developing glomerulus at the S-shaped body stage. These earliest cells …

Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability

AHJ Salmon, SC Satchell - The Journal of pathology, 2012 - Wiley Online Library
Appreciation of the glomerular microcirculation as a specialized microcirculatory bed, rather
than as an entirely separate entity, affords important insights into both glomerular and …

Estimating variance from high, low and closing prices

LCG Rogers, SE Satchell - The Annals of Applied Probability, 1991 - JSTOR
… ] is typically small, we shall assume that hx(s) is effectively constant through this interval and
since pt-s(O) = exp(-c2(t - s)/2o-2)/ V21ro2(t - s) is approximately (2iroU2(t - S))-1/2, we shall …

[PDF][PDF] Insulin signaling to the glomerular podocyte is critical for normal kidney function

…, R Lennon, DA Pons, RJ Owen, SC Satchell… - Cell metabolism, 2010 - cell.com
… We went on to explore the mechanism of insulin’s action on podocyte actin remodeling by
studying its effect on small GTPases. Using our in vitro human model, we found that insulin …

Modelling emerging market risk premia using higher moments

S Hwang, SE Satchell - International Journal of Finance & …, 1999 - Wiley Online Library
… Here, k1 is interpreted as the market’s marginal rate of substitution between skewness and
risk and k2 is the market’s marginal rate of substitution between kurtosis and risk. Therefore, …

A demystification of the Black-Litterman model: Managing quantitative and traditional portfolio construction

S Satchell, A Scowcroft - Forecasting expected returns in the financial …, 2007 - Elsevier
… distributions to individual’s views. We now review and extend BL’s results. We make the …
conditional upon the individual’s forecasts equals the individual’s forecast on average. This …

Glomerular endothelial glycocalyx constitutes a barrier to protein permeability

A Singh, SC Satchell, CR Neal… - Journal of the …, 2007 - journals.lww.com
Glycocalyx, composed of glycoproteins including proteoglycans, coats the luminal surface
of the glomerular capillaries. Human heparanase degrades heparan sulphate …

The Bernstein copula and its applications to modeling and approximations of multivariate distributions

A Sancetta, S Satchell - Econometric theory, 2004 - cambridge.org
… of Spearman’s rho as a function of the dependence parameter u in the approximation for
m … for the computation of Spearman’s rho for the KS copula can only be done numerically+ …

The human glomerular podocyte is a novel target for insulin action

…, J Yang, C Tasman, R Lennon, A Koziell, S Satchell… - Diabetes, 2005 - Am Diabetes Assoc
… A second normal human podocyte cell line was generated using the same technique
from the normal pole of a kidney removed for Wilm’s tumor. This cell line has been shown to …