The growth and survival of cells within tissues can be affected by ‘cell competition’ between
different cell clones. This phenomenon was initially recognized between wild-type cells and …

The basic Helix-Loop-Helix (bHLH) proteins represent a well-known class of transcriptional
regulators. Many bHLH proteins act as heterodimers with members of a class of ubiquitous …

… The phenotype suggests wgL mutations affect the shape of the segmental gradient, and
that this accounts for effects on pattern formation beyond the domain of transcription (Baker, …

The Drosophila retina has a precise repeating structure based on the unit eye, or ommatidium.
This review summarizes studies of the cell proliferation and survival episodes that affect …

Genetic mosaics that place cells in competition within tissues may model features of tissue
repair and tumor development and may reveal mechanisms of growth regulation. In one …

… This defect results from failure to establish the proper number and spacing of ommatidial
preclusters during the earliest stages of ommatidial assembly (NE Baker, M. Mlodzik, and GM …

… In NPP'/Y, cell death occurs close to the morphogenetic furrow (16, 28, and NE Baker,
unpublished data). Thus cell death might be responsible for early loss of N`P' ommatidia that form …

Segment polarity genes are expressed and required in restricted domains within each
metameric unit of the Drosophila embryo. We have used the expression of two segment polarity …

… Li and NE Baker, unpublished results). Further work will be required to determine
whether su(comp)3L-1 and su(comp)3L-2 affect components of a novel death pathway. …

wingless (wg) is a segment-polarity gene in Drosophila which is related to the murine proto-oncogene
inl-1. In Drosophila embryos, wg transcription defines part of each parasegment. …