Quorum sensing and quorum-quenching enzymes
… The rapid clearance of the AHL signal is attributed to the expression of AttM (Zhang et al.,
2002), … Dong, JL Xu, WJ Ng, and LH Zhang. 2003. Microbial diversity and prevalence of virulent …
2002), … Dong, JL Xu, WJ Ng, and LH Zhang. 2003. Microbial diversity and prevalence of virulent …
Quorum-quenching microbial infections: mechanisms and implications
The discovery of antibiotics early in the past century marked the beginning of active control
and prevention of infectious microbial diseases. However, extensive use of antibiotics has …
and prevention of infectious microbial diseases. However, extensive use of antibiotics has …
Quorum sensing and signal interference: diverse implications
Quorum sensing (QS) is a community genetic regulation mechanism that controls microbiological
functions of medical, agricultural and industrial importance. Discovery of microbial QS …
functions of medical, agricultural and industrial importance. Discovery of microbial QS …
Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase
…, LH Wang, JL Xu, HB Zhang, XF Zhang, LH Zhang - Nature, 2001 - nature.com
Bacterial cells sense their population density through a sophisticated cell–cell communication
system and trigger expression of particular genes when the density reaches a threshold. …
system and trigger expression of particular genes when the density reaches a threshold. …
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
A Brooks-Wilson, M Marcil, SM Clee, LH Zhang… - Nature …, 1999 - nature.com
Genes have a major role in the control of high-density lipoprotein (HDL) cholesterol (HDL-C)
levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage …
levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage …
AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora
…, JL Xu, XZ Li, LH Zhang - Proceedings of the …, 2000 - National Acad Sciences
N-acylhomoserine lactones, known as autoinducers (AIs), are widely conserved signal
molecules present in quorum-sensing systems of many Gram-negative bacteria. AIs are involved …
molecules present in quorum-sensing systems of many Gram-negative bacteria. AIs are involved …
[HTML][HTML] Genomewide association study of leprosy
…, YX Yu, Z Zhang, BQ Shi, LH Zhang… - … England Journal of …, 2009 - Mass Medical Soc
Background The narrow host range of Mycobacterium leprae and the fact that it is refractory
to growth in culture has limited research on and the biologic understanding of leprosy. Host …
to growth in culture has limited research on and the biologic understanding of leprosy. Host …
Acyl‐homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum‐quenching enzymes
N ‐acylhomoserine lactones (AHLs) are used as signal molecules by many quorum‐sensing
Proteobacteria. Diverse plant and animal pathogens use AHLs to regulate infection and …
Proteobacteria. Diverse plant and animal pathogens use AHLs to regulate infection and …
Comparative analyses of multi-species sequences from targeted genomic regions
…, KD Wetherby, LS Wiggins, AC Young, LH Zhang… - Nature, 2003 - nature.com
The systematic comparison of genomic sequences from different organisms represents a
central focus of contemporary genome analysis. Comparative analyses of vertebrate …
central focus of contemporary genome analysis. Comparative analyses of vertebrate …
Identification of Quorum-Quenching N-Acyl Homoserine Lactonases from Bacillus Species
…, AR Gusti, Q Zhang, JL Xu, LH Zhang - Applied and …, 2002 - Am Soc Microbiol
A range of gram-negative bacterial species use N-acyl homoserine lactone (AHL) molecules
as quorum-sensing signals to regulate different biological functions, including production of …
as quorum-sensing signals to regulate different biological functions, including production of …