Walking speed: the functional vital sign
A Middleton, SL Fritz, M Lusardi - Journal of aging and …, 2015 - journals.humankinetics.com
Walking speed (WS) is a valid, reliable, and sensitive measure appropriate for assessing
and monitoring functional status and overall health in a wide range of populations. These …
and monitoring functional status and overall health in a wide range of populations. These …
Landscapes of fear: spatial patterns of risk perception and response
Animals experience varying levels of predation risk as they navigate heterogeneous landscapes,
and behavioral responses to perceived risk can structure ecosystems. The concept of …
and behavioral responses to perceived risk can structure ecosystems. The concept of …
[PDF][PDF] Human germline genome editing
With CRISPR/Cas9 and other genome-editing technologies, successful somatic and
germline genome editing are becoming feasible. To respond, an American Society of Human …
germline genome editing are becoming feasible. To respond, an American Society of Human …
The design and construction of the ZEUS central tracking detector
…, MD Gibson, NA McCubbin, A Middleton… - Nuclear Instruments and …, 1994 - Elsevier
The mechanical, electrical and electronic design and construction of the ZEUS central tracking
detector are described, together with the chamber monitoring and environmental control. …
detector are described, together with the chamber monitoring and environmental control. …
Collective transport in arrays of small metallic dots
AA Middleton, NS Wingreen - Physical review letters, 1993 - APS
Collective charge transport is studied in one-and two-dimensional arrays of small normal-metal
dots separated by tunneling barriers. At temperatures well below the charging energy of …
dots separated by tunneling barriers. At temperatures well below the charging energy of …
Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity
…, DH Russell, EJ Donzis, AK Middleton… - Clinical cancer …, 2004 - AACR
The Akt kinase is a serine/threonine protein kinase that has been implicated in mediating a
variety of biological responses. Studies show that high Akt activity in breast carcinoma is …
variety of biological responses. Studies show that high Akt activity in breast carcinoma is …
[HTML][HTML] Genomic diagnosis of rare pediatric disease in the United Kingdom and Ireland
Background Pediatric disorders include a range of highly penetrant, genetically heterogeneous
conditions amenable to genomewide diagnostic approaches. Finding a molecular …
conditions amenable to genomewide diagnostic approaches. Finding a molecular …
[PDF][PDF] GA4GH: International policies and standards for data sharing across genomic research and healthcare
…, J Marshall, M Mattioni, A Metke-Jimenez, A Middleton… - Cell genomics, 2021 - cell.com
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical
advances by enabling the responsible sharing of clinical and genomic data through both …
advances by enabling the responsible sharing of clinical and genomic data through both …
[HTML][HTML] The Community Earth System Model (CESM) large ensemble project: A community resource for studying climate change in the presence of internal climate …
…, D Lawrence, K Lindsay, A Middleton… - Bulletin of the …, 2015 - journals.ametsoc.org
While internal climate variability is known to affect climate projections, its influence is often
underappreciated and confused with model error. Why? In general, modeling centers …
underappreciated and confused with model error. Why? In general, modeling centers …
Asymptotic uniqueness of the sliding state for charge-density waves
AA Middleton - Physical review letters, 1992 - APS
Analytic results are presented for the dynamic behavior of sliding charge-density waves (CDW’s)
and related extended nonlinear systems with randomness. It is shown that, in the limit …
and related extended nonlinear systems with randomness. It is shown that, in the limit …